Madecassoside is an active skin care ingredient derived from the Centella asiatica plant (often referred to by the pseudonym Asiatic pennywort and Gotu Kola). Centella asiatic, or more commonly, centella, is a medicinal plant that has been used for more than 2000 years in India and in Ayurvedic medicine. It has been used by many cultures for its curative properties in wound healing and for the anti-inflammatory benefits that it provides. Its edible leaves have been used to treat coughs and sinusitis, improve memory and help with liver disorders.
In recent years, extracts from Centella Asiatica have increasingly been included in skin care formulations thanks to their antioxidant-rich properties and ability to promote healing by accelerating skin cell production. Although Centella Asiatica extract is also rich in amino acids and beta carotene, its two components specifically make it a sought-after ingredient: asiaticoside and madecassoside.
Madecassoside for Wound Healing
The asiaticoside wound healing is triterpenine, a class of chemical compounds produced by plants as part of their self-defense mechanism. It is believed that asiaticoside increases the production of type I collagen, one of the main components of the skin and which helps the skin maintain a youthful appearance. The following is an eye opener: A 2011 study published in the journal Chemical Molecules found that centella extract stimulates collagen synthesis significantly better than vitamin C, one of our favorite and most reliable skin care heroes.
What does Madecassoside do?
Madecassoside, also classified as triterpenine, stimulates collagen type III production. While asiaticoside deals with the healing side of the wound, madecassoside separates itself from the packaging with anti-inflammatory properties, making it a popular ingredient for acne prone skin. In studies, Madecassoside has shown skin healing as well as anti-aging properties on the skin. It is estimated that it works in several ways including:
-Stimulates the synthesis of collagen I et III, an integral component of the skin.
-Reducing the activity of MMPs - metallic matrix proteins - or enzymes that play a role in the breakdown of the matrix or skin framework.
Madecassoside has shown several benefits in the treatment of psoriasis, most likely due to its anti-inflammatory properties.